Selected publications

Hao QL, George AA, Zhu Y, Barsky LW, Zielinska, E, Wang X, Price, M., Ge Shundi, Crooks GM. Human intrathymic lineage commitment is marked by differential CD7 expression: Identification of CD7neg lympho-myeloid thymic progenitors. Blood 2008;111: 1318-1326. PMCID: 2214748.

 

Abdel-Azim H, Zhu Y, Hollis R, Wang X, Ge S, Hao QL, Smbatyan G, Kohn DB, Rosol M, and Crooks GM. Expansion of multipotent and lymphoid-committed human progenitors through intracellular dimerization of Mpl. Blood 2008; 15:111(8):4064-74. PMID: 18174381. PMCID: PMC2288719.

 

Evseenko D, Schenke-Layland K, Dravid G, Zhu Y, Hao QL, Scholes J, Wang XC, MacLellan R, Crooks GM. Identification of the critical extracellular matrix proteins that promote human embryonic stem cell assembly. Stem Cells and Development, 2009. Jul.-Aug; 18 (6): 919-28. PMID: 19021502.

 

Cuddihy A, Ge S, Zhu Y, Jang J, Chidgey A, Thurston G, Boyd R, Crooks GM. VEGF-Mediated Cross-talk Within the Neonatal Murine Thymus. Blood, 2009 Mar. 19;113(12):2723-31. PMCID: PMC2661859.

 

Evseenko D, Zhu Y, Schenke-Layland K, Kuo J, Latour B, Ge, S, Dravid G, Li X, MacLellan WR, Crooks GM. Mapping the First Stages of Mesoderm Commitment During Differentiation of Human Embryonic Stem Cells. Proc Natl Acad Sci USA. 2010 Aug 3;107(31):13742-7.  PMCID: PMC2922221

 

Dravid G, Zhu Y, Scholes J, Evseenko D, Crooks GM. Dysregulated Gene Expression During Hematopoietic Differentiation from human Embryonic Stem Cells. Mol Ther. 2011 Apr;19(4):768-81. PMCID: PMC3070091

 

Andrade J, Ge S, Symbatyan G, Rosol MS, Arthur J. Olch AJ, Crooks GM. Effects of Sub-lethal Irradiation on Patterns of Engraftment after Murine Bone Marrow Transplantation. Biol Blood Marrow Transplant. 2011 May;17(5):608-19. PMCID: PMC3086732

 

Cuddihy AR, Suterwala B, Ge S, Kohn LA, Jang J, Andrade J, Wang X, Crooks GM. Rapid Thymic Reconstitution Following Bone Marrow Transplantation in Neonatal Mice is VEGF-Dependent. Biol Blood Marrow Transplant, 2012 May;18(5):683-9 PMCID: PMC3334422

 

Parekh C, Sahaghian A, Kim W, Scholes J, Ge S, Zhu Y, Asgharzadeh S, Hollis R, Kohn DB, Ji L, Malvar J, Wang X, Crooks GM. Novel Pathways to Erythropoiesis Induced by Dimerization of Intracellular cMpl in Human Myeloid-Erythroid Progenitors, Stem Cells 2012 April; 30 (4): 697-708. PMCID:PMC3973153

 

Kohn LA, Hao, Q-L, Sasidharan R, Parekh C, Ge S, Zhu Y, Mikkola HKA, Crooks GM. Lymphoid Priming in Human Bone Marrow Begins Prior to CD10 Expression with Up-Regulation of L-selectin, Nature Immunology 2012 Oct;13(10):963-71. PMCID: PMC3448017

 

Parekh C, Crooks GM. Critical Differences in Hematopoiesis and Lymphoid Development Between Humans and Mice. Journal of Clinical Immunology 2013 May;33(4):711-5. PMCID: PMC3633618

 

Corselli M, Chin CJ, Parekh C, Sahaghian A, Wang W, Ge S, Evseenko D, Wang X, Montelatici E, Lazzari L, Crooks GM, Péault B. Perivascular support of human hematopoietic stem/progenitor cells. BLOOD. 2013 Apr 11;121(15):2891-901. PMCID: PMC3707421

 

Evseenko D, Latour B, Richardson W, Corselli M, Sahaghian A,Cardinal S, Zhu Y, Chan R, Dunn B, Crooks GM. Lysophosphatidic Acid Mediates Myeloid Differentiation within the Human Bone Marrow Microenvironment. PLoS ONE 2013. 8(5): e63718. doi:10.1371/journal.pone.0063718 PMCID:PMC3655943

 

Kim WS, Zhu Y, Deng Q, Chin J, Grieco A, Dravid GG, Parekh C, Hollis RP, Lane T, Bouhassira E, Kohn DB, Crooks GM. Erythropoiesis from Human Embryonic Stem Cells Through Erythropoietin-Independent  AKT Signaling. Stem Cells. 32(6):1503-14, 2014. PMCID:PMC4037366

 

Chung B, Montel-Hagen A, Ge S, Zhu Y, Parekh C, Blumberg G, Arumugam B, Yang OO, Crooks GM. Engineering the Human Thymic Microenvironment to Support Thymopoiesis in Vivo, Stem Cells 32(9):2386-96, 2014. PMCID:PMC4138233.

 

Kohn LA, Seet CS, Scholes J, Codrea F, Chan R, Zaidi-Merchant S, Zhu Y, De Oliveira S, Kapoor N, Shah A, Abdel-Azim H, Kohn DB, Crooks GM. Human lymphoid development in the absence of common gamma chain receptor signaling. J Immunol. 2014 Jun 1;192(11):5050-8. PMCID: PMC4052377

 

Prashad SL, Calvanese V, Yao CY, Kaiser J, Sasidharan R, Crooks GM, Magnusson M, Mikkola HKA. GPI-80 Defines Self-renewal Ability in Hematopoietic Stem Cells during Human Development. Cell Stem Cell. 2014 Jan 8;16(1): 80-7. PMCID: PMC4520393

 

Casero D, Sandoval S, Seet CS, Scholes J,   Zhu Y, Ha VL, Luong A, Parekh C & Crooks GM. Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages. Nature Immunology. 2015 Dec; 16 (12):1282-91. PMCID PMC4653072

 

Chin CJ*, Cooper AR*, Lill GR, Evseenko D, Zhu Y, He CB, Casero D, Pellegrini M, Kohn DB, Crooks GM. Genetic Tagging In Human Mesoderm Revealed Tripotent Lateral Plate Mesodermal Progenitors. Stem Cells. 34(5):1239-50. 2016. PMCID: PMC5052131

 

Seet CS, He C, Bethune MT, Li S, Chick B, Gschweng EH, Zhu Y, Kim K, Kohn DB, Baltimore D, Crooks GM* & Montel-Hagen A*. Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids. Nature Methods. 2017.